NK VUE artificially activates the NK cells in the blood using our patented NK Cell activator (Promoca) and measures the amount of Interferon gamma secreted using the method of enzyme-linked immunosorbent assay (ELISA).
This test measures the amount of Interferon gamma (IFN-γ) secreted after artificially activating NK cells in the blood.
It can help evaluate your body’s natural immunity against cancer or other diseases.
NK VUE is much simpler to use compared to the conventional NK cell activity tests.
|Conventional methods||NK Vue® method|
|Flow cytometric Assay||Chromium-51 Release Assay||Flow cytometric Assay
(CD107a degranulation assay)
|NK Vue® Kit|
|Object||NK cell number counting||NK cell cytotoxicity||NK cell cytotoxicity||NK cell activity|
|Marker||CD3, CD16/56||51Cr (radioisotope)||CD3, CD16/56, CD107a||IFN-γ|
|Blood collection||2mL||Variable depends on NK cell number||Variable depends on NK cell number||1mL|
|Sample Type||PBMC||PBMC or lymphocytes||PBMC||Whole blood|
|Disadvantage||Only the relative percentage (%)
of NK cells can be measured
-Complicated experiments & low reproducibility
-Expensive and time consuming
|Sensitivity and reproducibility may vary depending on the number of cells||-|
The following conditions or drugs have been known to temporarily affect immune cell function and significantly influence the test results:
Viral or bacterial infection / Autoimmune diseases. / Immunosuppressive drugs. / Acute Stress or Severe fatigue Sleep Disorders / Steroid-based drugs