NK VUE artificially activates the NK cells in the blood using our patented NK Cell activator (Promoca) and measures the amount of Interferon gamma secreted using the method of enzyme-linked immunosorbent assay (ELISA).
This test measures the amount of Interferon gamma (IFN-γ) secreted after artificially activating NK cells in the blood.
It can help evaluate your body’s natural immunity against cancer or other diseases.
Clinical trial: 2011-2012, Yonsei University Severance Hospital Clinical Test Center
NK VUE is much simpler to use compared to the traditional NK cell activity tests.
Traditional methods | NK Vue methods | |||
---|---|---|---|---|
Flow cytometric Assay | Chromium-51 Release Assay | Flow cytometric Assay (CD107a degranulation assay) |
NK Vue® | |
Object | NK Cell Number Counting | NK Cell Cytotoxicity | NK Cell Cytotoxicity as % | NK Cell Activity as a number |
Marker | CD3, CD16/56 | Chromium-51 | CD3, CD16/CF56, CD107a | IFN-γ |
Blood Collection | 2ml | Variable Depends on NK Cell Number | Variable Depends on NK Cell Number | 1ml |
Disadvantage |
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|
|
- |
Sample Type | Purified PBMC | Purified PBMC Cultured lymphocytes | Purified PBMC | Whole Blood |
Period | 5 hours | 5-7 days | 10 hours | 24-28 hours (Including of 20-24 hours Incubating) |
Accuracy | Depends on Researcher | Depends on Researcher | Depends on Researcher | Digitize through ELISA |
Pre-
screening
Immunity
Benchmark
Complementary
Diagnosis
Treatment
Monitoring
The following conditions or drugs have been known to temporarily affect immune cell function and significantly influence the test results:
Viral or bacterial infection / Autoimmune diseases. / Immunosuppressive drugs. / Acute Stress or Severe fatigue Sleep Disorders / Steroid-based drugs